Doyle's Cafe's authentic, old-school Boston charm made it a natural choice for filmmakers seeking a genuine local backdrop. Over the decades, the pub appeared in several prominent Hollywood productions, solidifying its place in popular culture. Most notably, scenes from the Clint Eastwood-directed 'Mystic River' (2003) were filmed within its historic walls.
Source: Wikipedia, “Doyle's Cafe”; American Film Institute, AFI Catalog of Feature Films, Mystic River (2003)